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Home > Dysphagia

Dysphagia

Also known as dysphagia or swallowing dysfunction, this symptom is experienced by approximately 22% of adults age 60 or older. Patients with dysphagia experience difficulties in swallowing liquid and food, which is usually accompanied by other symptoms such as coughing, choking, esophageal or nasal reflux, or drooling while eating. This condition may cause neurological disorders or physical blockage.

Reference: ICD-11, WHO,2019, Ver. 04

Xerostomia

Xerostomia is a common symptom1) expreincd by about 70% of elderly patients with cognitive disorder. Many older people feel discomfort and pain when swallowing beverages due to dysphagia. In cognitive disorders, xerostomia is cause by chronic dehydration, 2)which is a result of failure to recognize thirst caused by a lack of water in the body. These conditions should be sufficiently considered in order to improve convenience of administration.

References
1) Gil-Montoya, J.A., Barrios, R., Sánchez-Lara, I. et al. Prevalence of Drug-Induced Xerostomia in Older Adults with Cognitive Impairment or Dementia: An Observational Study. Drugs Aging 33, 611-618 (2016)
2) Xerostomia (Dry Mouth) and Alzheimer's. Alzheimer's Association. Dec 15, 2016

Formulations that are comfortable to administer

According to the NCHS Data Brief, 85% of the elderly population has taken medication within the last 30 days. With the accelerated hyper-aging of society, the elderly population keeps increasing, which means that the number of older people who should take medication even with dysphagia, is also increasing. As the demand for easily administrable formulations is gradually increasing, the demand for OD!FS® as a specialized formulation for older people will also be likely to grow.

Proportions of people who have administered ETC drug at least once within the last 30 days by age group


The elderly, mainstream of the population

Most countries in the world have entered the aging era, in which 7% or more of the population is aged 65 or older. In Japan, 20% of the population is senior citizens. By 2030, one in three citizens will be aged 65 years or older. But this is not an issue that is exclusive to Japan. The United Nations has reported that rapid aging will be in progress in developed countries with high consumption. Within 10 years, these countries will experience a demographic shift, in which 20% of the population will be age 65 or older. This report forecast that 22% of the entire population in developed countries will be 65 years or older by 2030, while 22.9% of the population in developing countries will be 65 or older by 2030.

Reference: World Population Ageing 2019, United Nations, 2019

Composition of global population (1990 to 2050)


Why should we prepare formulations for the elderly?

A report by the UNECE (United Nations Economic Commission for Europe) commented “The elderly should be recognized as mightily important consumers. ”Forbes has forecast that worldwide, consumption by those age 60 or older will amount to approximately 15 trillion dollars in 2020, which is 5 times more than the GDP of the United Kingdom (2019).

References
1) Older Persons as Consumers, UNECE Policy Brief on Ageing, May 2009, No. 3
2) Aging Populations: A Blessing For Business, Paul Irving, Forbes, Feb 23, 2018

The 2019 World Economic Forum mentioned aging in developed countries, including South Korea. Significantly, the Forum predicted that South Korea will surpass Japan and top the world in terms of the population of senior citizens to the whole population in the near future. This is why South Korea has come to the center of attention as a test market before advancing to the markets for the elderly with respect of the sizes of economy and population.