In South Korea, the approximate number of dementia patients aged 65 years or older was 750,000 in 2018, but it is now estimated that this number will reach one million by 2030.
Trends of the number and prevalence of dementia patients age 65 or older (2018-2060)
Status of South Korean Market (Ref. UBIST)
Major trends in dementia treatment and need for OD!FS®
Increased number of dementia patients due to the increase in the elderly population
Changes in patterns of hospitalization and long-term caused by the increase in single-person household (*Dysphagia is commonly found in hospitalized patients)
Demand for Donepezil HCl in a brand-new formulation, which can be easily swallowed with a minimal effort, lying in bed, just prior to retiring (*Against dysphagia or xeroderma)
Since dementia patients don’t feel thirsty well, which causes dry mouth and dry skin, ODT or film type is not very suitable (*Xerostomia: dry mouth) and so is DDS patch (*May cause skin allergy or itching).
Tablets may have a risk of aspiration pneumonia when the patients with dysphagia drink water for administration while suspension syrup is not easy as well.
Immensely bitter taste of Donepezil HCl substance: Alteration of salt form may involve a regulatory issue while powder / ODT / film are not perfect in taste-masking.
OD!FS® allows resistance-free administration and comfortable & easy swallowing without the need of water while it requires only the least amount of saliva.
Demand in prescriptions of Donepezil HCI
Such side effects begin in 2-3 hours after taking Donepezil. So it is recommended to take Donepezil in the evening, just prior to retiring.